Mental Performance – Premium Brain Booster for Focus & Memory with Cognizin Citicoline

Scientific References

N-Acetyl- L-Tyrosine 300mg

Tyrosine is an essential amino acid in the body and brain functions. The form of N-Acetyl L-Tyrosine supplied by Mental Performance is one of the most stable and suitable for oral ingestion. It improves mood, cognitive performance, and memory. These benefits are largely due to its ability to increase the availability of dopamine, a neurotransmitter active in the brain that improves mood and cognitive performance.

A study in 2017 found a strong link between tyrosine intake and these functions by studying a group of 1724 young and older adults. They found that people with higher tyrosine intakes had better fluid intelligence, which is the ability to think logically and adapt to find solutions to problems in new or stressful situations. (1)

Tyrosine’s efficacy has been proven in military personnel who work more than 12 hours a day. A review of several medical studies concluded that tyrosine may counteract the decline in performance and deterioration of mood associated with stress, sleep deprivation, and fatigue in military workers. (2)

Even after 24 hours of sleep deprivation, tyrosine lowers fatigue, enhances stamina, and regulates mood during night work. (3)

The ability of tyrosine to increase the level of the neurotransmitter norepinephrine in the brain explains this benefit. This neurotransmitter’s level diminishes as a result of exhaustion and stress. Tyrosine can help with this issue by reducing tension and enhancing performance and energy. (4)

A set of ten men and ten women were given 150 mg/kg L-tyrosine or a placebo in a trial. They were then asked to complete a series of complicated activities requiring a variety of cognitive skills (remembering shapes and words, making complex choices, etc.). L-tyrosine significantly increased accuracy and multitasking abilities. According to the findings, ingesting tyrosine can help people perform better at work in stressful situations where they must do numerous tasks at once while using a variety of skills (solving arithmetic problems, remembering shapes, colors, numbers, and words, etc.). (5)

Cognizin®  Citicoline 250 mg

Cognizin® is a patented version of citicoline, one of the key precursors for membrane phospholipid synthesis. Phospholipids are the building blocks of the central nervous system’s cells. Citicoline thus plays a structural role in the brain. This molecule has been proven in studies to enhance neuron renewal, making it a good neuroprotective and neuroreparative agent.(6)

Memory, thinking, decision-making, and creativity are all controlled by the frontal lobe. Citicoline improves mental capacities, especially memory, by optimizing energy metabolism in this area of the brain (7)

In a 2001 study, 100 healthy men and women aged 50 to 85 who had age-related memory impairment (AAMI) were divided into 2 groups. One group was given a placebo for 12 weeks, while the other was given 500 mg of citicoline every day. The researchers noticed that citicoline group showed better episodic memory (memory for dates and places, and long-term memory). They concluded that citicoline use improved memory in general.8)

According to a recent US-Japanese study, Cognizin® improves brain function in teenagers. For the trial, 75 male teens were assigned randomly into two groups. The first group was given either 250 or 500 mg of citicoline per day for 28 days, whereas the second was given a placebo. Researchers found a significant improvement in attention, psychomotor speed, and a decrease in impulsivity in youth who received Cognizin® versus those who received a placebo. (9)

L-Theanine 100 mg                                      

Caffeine and theanine, in combination, boost attention and concentration in healthy individuals (10). A study found that giving 2.5 mg/kg body weight of L-theanine and 2.0 mg/kg caffeine increased performance on a task that required sustained visual attention, suggesting that this combination may help to prevent mental wandering during tasks. (11)

A dose of 100.6 mg of L-theanine led to a reduction in reaction time, an increase in the rate of correct answers, and an improvement in working memory in healthy patients aged 50 to 69, according to a Japanese study. (12)

Guarana seed powder extracts 100 mg

Guarana is a herb that Amazonian Amerindians used to fight hunger and exhaustion. It is nowadays a key component in many energy drinks and supplements that boost energy and endurance.

According to a British study, guarana extract combined with vitamins and minerals improves cognitive performance, the ability to perform intellectual tasks, increases task speed and accuracy, and lowers mental fatigue caused by long work hours. (13) The low caffeine concentration in the guarana extract used in this study led the researchers to assume that the plant’s effects are due to more than just caffeine and that other components have their own effects as well. (14)

The caffeine in guarana extract complements the characteristics of the other compounds in the plant. As a result, the guarana extract in Mental Performance enhances mental tiredness, physical and mental performance, alertness and attention, response speed, arousal and energy levels, and memory. (15) These properties are helpful for students who study long hours, and night workers who want to work longer and boost their endurance.

Bacopa monnieri 75 mg

Bacopa monnieri is a medicinal plant used to promote focus, mental alertness, and memory in Ayurvedic medicine. This plant’s active constituent, bacoside, has been found in scientific studies to help with memory.16)

The plant’s ability to enhance blood flow to the brain, its neuroprotective antioxidant capability, and its improvement of neurotransmitter function all contribute to its memory-enhancing effects. (17)

In an Australian study, 76 healthy adults aged 40 and 65 were divided into two groups. For three months, the first group received a daily weight-based dose of Bacopa monnieri, while the second received a placebo. The researchers saw a decrease in the incidence of forgetfulness during memory tests in the patients who got Bacopa monnieri. (18)

A randomized, double-blind, placebo-controlled trial in Australia has shown that Bacopa monnieri improves memory in healthy elderly people. Some of the study participants received 300 mg of Bacopa monnieri daily for 12 weeks. Some others received a placebo. The researchers found a significant improvement in memory and learning ability in the subjects who received the Bacopa extract compared to those who received the placebo. (19)

Magnesium 60 mg 

Magnesium is a critical cation for the nervous system. It has neuroprotective effects and plays a crucial function in nerve impulse transmission. Magnesium intake has been shown to improve cognitive function in vitro experiments. (20).

In addition, it has been demonstrated that when magnesium is mixed with citicoline, the positive effects of magnesium are amplified. (21)

Vitamin C 40 mg 

Vitamin C levels in the body are linked to improved performance on memory, concentration, attention, decision-making, and execution speed. Adults with optimal vitamin C plasma levels have been shown to have better cognitive performance. (22)

Vitamin C might help you stay motivated to complete tasks. It also reduces anxiety and the stress response while performing a task. (23)

Vitamin B5 Pantothenic Acid 6 mg

Vitamin B5 or Pantothenic Acid is essential for normal brain function. It catalyzes energy production and improves blood flow in this organ. It is the substrate for the synthesis of coenzyme A (CoA), which is involved not only in oxidative metabolism but also in the structure and function of brain cells. (24) Vitamin B5 is also important for the synthesis, release, and function of many neurotransmitters essential for brain function and maintenance of cognition. (25)

Because of the critical involvement of vitamin B5 in brain physiology, it is a necessary component for normal mental performance. The vitamin supports memory, reasoning, decision-making, and endurance when completing intensive intellectual work. (26) (27)

Zinc 3 mg 

Zinc is essential in the physiology of neurons and has a protective antioxidant role in the central nervous system. This element deficiency causes neurological and cognitive issues, with memory and learning being notably affected. Zinc, in adequate doses, can contribute to the healthy functioning and maintenance of the brain. (28)

Vitamins B6 (0,7 mg) and B12 (1.2µg) 

Numerous studies have linked adequate vitamin B6 and B12 intake with improved memory development.

When scientists examined data on the dietary habits of 3136 young men and women in 1985 and 1986, they found 25 years later that subjects who consumed vitamins B6 and B12 between the ages of 18 and 30 had better cognitive performance, including concentration and memory. (29)

Vitamin B9 Folic Acid (100µg) 

Folic acid, or vitamin B9, is an essential nutrient for normal brain function. Over six months, patients with mild cognitive impairment were given a combination of folic acid and vitamin B12, which was demonstrated to improve cognitive performance significantly. (30)

Citicoline: A Superior Form of Choline?

1. Kyowa Hakko USA Announces GRAS Self-Affirmation for Novel Brain Health Ingredient Cognizin Citicoline. [(accessed on 20 September 2014)]; Available online: http://www.kyowa-usa.com/news/2009/05-28.html.
2. Commission Implementing Decision of 1 July 2014 Authorising the Placing on the Market of Citicoline as a Novel Food Ingredient under Regulation (EC) No 258/97 of the European Parliament and of the Council. [(accessed on 7 June 2019)]; Available online: https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX%3A32014D0423.
3. Regulation E.C. No 1924/2006 of the European Parliament and of the Council of 20 December 2006 on Nutrition and Health Claims Made on Foods. Off. J. Eur. Union. 2007;12:3–18. [Google Scholar]